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DL-Penicillamine

CAS：52-66-4

产品活性：DL-Penicillamine is a chelating agent recommended for the removal of excess copper in patients with Wilson´s disease. DL-Penicillamine is only found in individuals that have used or taken this drug. It is the most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson´s disease. From in vitro studies which indicate that one atom of copper combines with two molecules of DL-penicillamine. DL-Penicillamine also reduces excess cystine excretion in cystinuria. This is done, at least in part, by disulfide interchange between DL-penicillamine and cystine, resulting in the formation of penicillamine-cysteine disulfide, a substance that is much more soluble than cysteine and is excreted readily. DL-Penicillamine interferes with the formation of cross-links between tropocollagen molecules and cleaves them when newly formed. The mechanism of action of DL-penicillamine in rheumatoid arthritis is unknown although it appears to suppress disease activity. Unlike cytotoxic immunosuppressants, DL-penicillamine markedly lowers IgM rheumatoid factor but produces no significant depression in absolute levels of serum immunoglobulins. Also unlike cytotoxic immunosuppressants which act on both, DL-penicillamine in vitro depresses T-cell activity but not B-cell activity.

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品牌介绍：
☆ TargetMol品牌专业提供各领域信号通路小分子抑制剂、拮抗剂、天然产物、药物筛选化合物。
☆ 产品适应在癌症、免疫学、心血管系统、呼吸、神经科学等多项科学领域的研发使用，超过660万种小分子化合物。
☆ 提供20000多个小分子抑制剂、天然产物和200多个化合物库。
☆ 配备完善的化学合成和生物实验室，可分别提供高品质小分子抑制剂和药物筛选技术服务。
☆ 每批产品都有严格的NMR和HPLC技术检测，以保证产品高纯度高质量。

原创作者：上海陶术生物科技有限公司