简介内容:BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor (IC50: 66 nM; Kd: μM). BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC50: 515 nM).
产品介绍:Methyl analog of DEXTRORPHAN that shows high-affinity binding to some areas of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (receptors, N-METHYL-D-ASPARTATE) and a non-competitive channel blocker. It is one of the extensively used antitussives and is also used in the research of the relationship of glutamate receptors with neurotoxicity.
品牌介绍: TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿,致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol品牌的客户群分布于40多个国家和地区,已发展成为全球的化合物库和小分子化合物研究供应商。