简介内容:TH287 is a selective MTH1 inhibitor(IC50 : nM). It causees incorporation of oxidized dNTPs in cancer cells, leading to DNA damage, cytotoxicity and therapeutic responses in patient-derived mouse xenografts.
产品介绍:ARS-1323-alkyne is a switch-II pocket (S-IIP) inhibitor and a conformational specific chemical reporter of KRASG12C nucleotide state in living cells.
品牌介绍: TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿,致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol品牌的客户群分布于40多个国家和地区,已发展成为全球的化合物库和小分子化合物研究供应商。