简介内容:3PO is a small-molecule inhibitor of PFKFB3 (IC50: μM), inhibiting the proliferation of several human malignant hematopoietic and adenocarcinoma cell lines (IC50: μM). It suppresses glucose uptake, and decreases the intracellular concentration
产品介绍:BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor (IC50: 66 nM; Kd: 4.8 μM). BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC50: 515 nM).
品牌介绍: TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿,致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol品牌的客户群分布于40多个国家和地区,已发展成为全球的化合物库和小分子化合物研究供应商。