简介内容:DS-7423 is a small-molecule dual inhibitor of phosphatidylinositol-3-kinase (PI3K) and mammalian target of rapamycin (mTOR). Although DS-7423 potently inhibits PI3Kα (IC50?=? nM) and mTOR (IC50?=? nM), it also inhibits other isoforms of class I PI