简介内容:CZC-54252 hydrochloride is a potent and selective LRRK2 inhibitor with IC 50 s of nM and nM for wild-type and G2019S LRRK2 , respectively. G2019S LRRK2 -induced human neuronal injury is attenuated by CZC-54252 hydrochloride with an EC 50 of ~1 n