简介内容:GKI-1 is a Greatwall (GWL) kinase inhibitor with IC 50 s of and μM against hGWL FL and hGWL-KinDom, respectively. Greatwall (GWL) has been proposed as a novel cancer therapy target. GKI-1 robustly inhibits ROCK1 with an IC 50 of 11 μM, but only weakly affected PKA [1].
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GKI-1GKI1,GKI 1
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产品名称:GKI-1 CAS:2444764-03-6 产品介绍:GKI-1 is a Greatwall (GWL) kinase inhibitor with IC 50 s of 4.9 and 2.5 μM against hGWL FL and hGWL-KinDom, respectively. Greatwall (GWL) has been proposed as a novel cancer therapy target. GKI-1 robustly inhibits ROCK1 with an IC 50 of 11 μM, but only weakly affected PKA [1].
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