CHMFL-PI3KD-317；化合物CHMFL-PI3KD-317CHMFL-PI3KD-317T10804

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产品名称：CHMFL-PI3KD-317；化合物CHMFL-PI3KD-317CHMFL-PI3KD-317
产品型号：T10804
产品产地：中国大陆
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简介内容：CHMFL-PI3KD-317 is a highly potent, selective and orally active PI3Kδ inhibitor, with an IC50 of 6 nM, and exhibits over 10-1500 fold selectivity over other class I, II and III PIKK family isoforms, such as PI3Kα (IC50, nM), PI3Kβ (IC50, 284 nM), PI3Kγ (IC50, nM), PIK3C2A (IC50, >10000 nM), PIK3C2B (IC50, nM), VPS34 (IC50, nM), PI4KIIIA (IC50, nM) and PI4KIIIB (IC50, nM). CHMFL-PI3KD-317 inhibits PI3Kδ-mediated Akt T308 phosphorylation in Raji cells, with an E

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原创作者：上海陶术生物科技有限公司

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