简介内容：GKI-1 is a Greatwall (GWL) kinase inhibitor that inhibits hGWLFL with an IC50 of . GKI-1 also inhibited hGWL-KinDom, and its IC50 was ?M. The inhibitory effect of GKI-1 on ROCK1 was better than that of hGWLFL and hGWL-KinDom, and its IC50 was 11 ?M, which only weakly inhibited PKA.
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