SB-657510；化合物SB-657510SB-657510T12848 - 上海陶术生物科技有限公司

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产品名称：SB-657510；化合物SB-657510SB-657510
产品型号：T12848
产品产地：中国大陆
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简介内容：SB-657510 is a urotensin II (UII) receptor (UT) antagonist. The Ki values of UT for human, monkey, cat, rat and mouse were 61, 17, 30, 65 and 56 nM, respectively. SB-657510 plays an anti-inflammatory role by inhibiting UII-induced inflammatory mediators, such as adhesion molecules, in human vascular endothelial cells and upregulation of cytokines and tissue factors. SB 657510 has a therapeutic effect on diabetes-related atherosclerotic disease in diabetic mouse models.

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原创作者：上海陶术生物科技有限公司

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