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(S,R,S)-AHPC-Me dihydrochloride;化合物 T13671LVHL ligand 2 dihydrochloride|||E3 ligase Ligand 1 dihydro
 
 
  • 产品名称:(S,R,S)-AHPC-Me dihydrochloride;化合物 T13671LVHL ligand 2 dihydrochloride|||E3 ligase Ligand 1 dihydro
  • 产品型号:T13671L
  • 产品产地:中国大陆
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  • 简介内容:(S,R,S)-AHPC-Me dihydrochloride, also known as VHL ligand 2 dihydrochloride, is a chemical compound utilized in the synthesis of ARV-771. ARV-771, a BET PROTAC degrader relying on von Hippel-Landau (VHL) E3 ligase, demonstrates potent degradation of BET protein in castration-resistant prostate cancer (CRPC) cells, with a DC50 of less than 1 nM. This compound serves as the VHL ligand, specifically the (S,R,S)-AHPC-based VHL ligand, that facilitates the recruitment of von Hippel-Lindau (VHL) prote
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(S,R,S)-AHPC-Me dihydrochloride;化合物 T13671LVHL ligand 2 dihydrochloride|||E3 ligase Ligand 1 dihydro

标签:化合物   T13671L   

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