Lometrexol；洛美曲索LY 264618|||DDATHF；LY 264618|||DDATHFT15826

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产品名称：Lometrexol；洛美曲索LY 264618|||DDATHF；LY 264618|||DDATHF
产品型号：T15826
产品产地：中国大陆
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简介内容：Lometrexol (LY 264618), an antipurine Antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol can further inhibit de novo purine synthesis, causing abnormal cell proliferation and Apoptosis, even cell cycle arrest. Lometrexol has anticancer activity. Lometrexol also is a potent human Serine hydroxymethyltransferase1/2 (hSHMT1/2) inhibitor.

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原创作者：上海陶术生物科技有限公司

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