ACBI1；化合物ACBI1ACBI1T17350 - 上海陶术生物科技有限公司

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产品名称：ACBI1；化合物ACBI1ACBI1
产品型号：T17350
产品产地：中国大陆
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简介内容：ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50s of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 can induce anti-proliferative effects and apoptosis.

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原创作者：上海陶术生物科技有限公司

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