简介内容:UMB-32 is a potent and selective BRD4 inhibitor, demonstrating an affinity for BRD4 with a dissociation constant (K d) of 550 nM and an inhibitory concentration 50 (IC 50) of 637 nM. Moreover, UMB-32 exhibits effectiveness against TAF1, a bromodomain-containing transcription factor [1].