G36；化合物G36G-36；G-36T22794 - 上海陶术生物科技有限公司

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产品名称：G36；化合物G36G-36；G-36
产品型号：T22794
产品产地：中国大陆
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简介内容：G36 is a cell-permeable non-steroidal antagonist of GPER. G36 inhibits activation by either 17β-estradiol or the GPER-selective agonist G-1 (IC50 = 112 and 165 nM, respectively). G36 has no detectable binding activity to either ERα or ERβ. G36 blocks the activation of PI3K or calcium mobilization triggered by estrogen through GPER and it suppresses ERK activation by estrogen or G-1 but not by EGF. G-36 can be used in combination with GPER-selective agonists, like G-1, to distinguish the roles of

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原创作者：上海陶术生物科技有限公司

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