简介内容:Bencycloquidium Bromide is a muscarinic M3 antagonist. Bencycloquidium bromide inhibits nasal hypersecretion in a rat model of allergic rhinitis. Bencycloquidium Bromide showed high affinity toward the M(3) receptor in Chinese hamster ovary (CHO) cells (M(1) pKi=, M(2) pKi=, M(3) pKi=); pA(2)=, and in methacholine-induced contraction of trachea, ileum and urinary bladder, in methacholine-induced bradycardia of right atrium in vitro, respectively.