简介内容:BMS-933043 is a Selective α7 nAChR partial agonist. BMS-933043 showed potent binding affinity to native rat (Ki = nM) and recombinant human alpha7 nicotinic acetylcholine receptors (Ki = nM). BMS-933043 shows agonist activity in a calcium fluorescence assay (EC50 = nM) and whole cell voltage clamp electrophysiology (EC50 = μM (rat) and μM (human)).