简介内容:JNJ-2408068 is an inhibitor of respiratory syncytial virus (RSV). JNJ-2408068 exhibited potent antiviral activity with EC50 of nM. A similar inhibitory effect was observed in a RSV-mediated cell fusion assay (EC50= nM). JNJ-2408068 interferes with RSV fusion through a mechanism involving a similar interaction with the F protein.