简介内容：LEI-101 is a potent, selective, and orally bioavailable cannabinoid CB2 receptor agonist, with a pEC 50 of 8 for hCB2, and a pK i of less than 4 for hERG. LEI-101 is ~100-fold more potent in binding to CB2 receptors than to CB1 receptors. LEI-101 has therapeutic potential in diseases that are associated with inflammation and/or oxidative stress, including kidney disease [1] [2].
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