Setipiprant；塞替匹仑KYTH-105|||ACT-129968；KYTH-105|||塞替匹仑|||ACT-129968T3520

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产品名称：Setipiprant；塞替匹仑KYTH-105|||ACT-129968；KYTH-105|||塞替匹仑|||ACT-129968
产品型号：T3520
产品产地：中国大陆
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简介内容：Setipiprant (ACT-129968) is an orally available, selective CRTH2 antagonist (IC50: nM). CRTH2 is a G protein-coupled receptor for prostaglandin (PGD2). PGD2 is produced by the mast cells and is a key mediator in various inflammatory diseases, including allergy and asthma. Binding of PGD2 to CRTH2, which are expressed on the surface of blood-borne cells, induces chemotaxis of Th2 cells, basophils, and eosinophils, and stimulates cytokine release from these cells.

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原创作者：上海陶术生物科技有限公司

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