uPSEM 792 hydrochloride；uPSEM 792 hydrochlorideuPSEM 792 hydrochlorideT36810

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产品名称：uPSEM 792 hydrochloride；uPSEM 792 hydrochlorideuPSEM 792 hydrochloride
产品型号：T36810
产品产地：中国大陆
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简介内容：Ultrapotent PSEM (uPSEM) agonist for PSAM4-GlyR and PSAM4-5HT3 (Ki = nM for PSAM4-GlyR and <10 nM for PSAM4-5HT3). Exhibits >10,000-fold agonist selectivity for PSAM4-GlyR over α7-GlyR, α7-5HT3, and 5HT3-R, and 230-fold selectivity over α4β2 nAChR. Also weak partial agonist (~10 %) at α4β2 nAChR. Retains the potency of varenicline for PSAM4-GlyR with enhanced chemogenetic selectivity. Does not act as a substrate for P-glycoprotein pumps. Silences neurons in vivo. Brain-penetrant.

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名称: uPSEM 792 hydrochloride；uPSEM 792 hydrochloride

描述: uPSEM 792 hydrochloride。

关键字: uPSEM 792 hydrochloride |

原创作者：上海陶术生物科技有限公司

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