D-erythro-MAPPD-erythro-MAPPD erythro MAPP|||DerythroMAPPT37056

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产品名称：D-erythro-MAPPD-erythro-MAPPD erythro MAPP|||DerythroMAPP
产品型号：T37056
产品产地：中国大陆
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简介内容：D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 μM) as well as the serine/threonine protein phosphatase CAPP at concentrations up to 10 μM. D-erythro-MAPP increases intracellular ceramide levels, induces cell cycle arrest at the G0/G1 phase, and inhibits growth of HL-60 promyelocytic leukemia cells in a time- and concentration-dependent manner.

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Bioactivity

名称: D-erythro-MAPPD-erythro-MAPP

描述: D-erythro-MAPP。

关键字: D erythro MAPP |DerythroMAPP |

原创作者：上海陶术生物科技有限公司

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