简介内容：Ru360, an oxygen-bridged dinuclear ruthenium amine complex, is a selective mitochondrial calcium uptake inhibitor. Ru360 potently inhibits Ca2+ uptake into mitochondria with an IC50 of nM. Ru360 binds to mitochondria with high affinity (Kd of nM). Ru360 has antiarrhythmic and cardioprotective effects[1][2].
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