简介内容:D-DOPA is an enantiomer of the dopamine precursor L-DOPA . It can be converted to L-DOPAviasequential oxidation and transamination, which are mediated by D-amino acid oxidase (DAAO) and DOPA transaminase, respectively, in rat kidney reduces the number of dopaminergic neurons in primary rat embryonic mesencephalic cultures in a concentration-dependent administration of D-DOPA (200 μg/animal) increases striatal dopamine levels in (20 mg/kg,