简介内容：HSGN-218 is a gut-restrictive is active againstC. difficile(MIC = μg/ml) and clinical isolates ofC. difficile(MICs = μg/ml) and is not cytotoxic to Caco-2 cells when used at concentrations ranging from 4 to 64 μg/ml. HSGN-218 (50 mg/kg) increases survival and protects mice fromC. difficilerecurrence in mouse models ofC. difficileinfection.
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