简介内容:BE-24566B is a polyketide fungal metabolite originally isolated fromS. is active againstB. subtilis,B. cereus,S. aureus,M. luteus,E. faecalis, andS. thermophilus(MICs = , , , , , and μg/ml, respectively). BE-24566B is an endothelin (ET) receptor antagonist (IC50s = 11 and μM for ETAand ETBreceptors, respectively).2