Telaglenastat hydrochlorideTelaglenastat hydrochlorideCB-839 hydrochlorideT39309

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产品名称：Telaglenastat hydrochlorideTelaglenastat hydrochlorideCB-839 hydrochloride
产品型号：T39309
产品产地：中国大陆
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简介内容：Telaglenastat (CB-839) hydrochloride is a first-in-class, reversible, and orally active inhibitor of glutaminase 1 (GLS1). It selectively inhibits the splice variants of GLS1, specifically KGA (kidney-type glutaminase) and GAC (glutaminase C), as compared to GLS2. Telaglenastat hydrochloride has an IC50 of 23 nM for endogenous glutaminase in mouse kidney and 28 nM in the brain. In addition, it induces autophagy and exhibits antitumor activity.

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名称: Telaglenastat hydrochlorideTelaglenastat hydrochloride

描述: Telaglenastat hydrochloride。

关键字: CB-839 hydrochloride |

原创作者：上海陶术生物科技有限公司

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