CC-99677；化合物CC-99677CC99677|||Gamcemetinib|||CC 99677；CC99677|||Gamcemetinib|||CC 99677T39321

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产品名称：CC-99677；化合物CC-99677CC99677|||Gamcemetinib|||CC 99677；CC99677|||Gamcemetinib|||CC 99677
产品型号：T39321
产品产地：中国大陆
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简介内容：CC-99677 (Gamcemetinib) is a selectively targeted covalent MAPKAPK2 (MK2) inhibitor for autoimmune diseases that translates biochemical potency into cellular potency as demonstrated by potent inhibition of heat shock protein 27 (HSP1) phosphorylation in LPS-activated monocyte THP-27 cells via a nucleophilic aromatic substitution (SNAr) in Rat experiments demonstrated potency in both biochemical (IC 50 = nM) and cellular assays (EC 50 =89 nM).

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原创作者：上海陶术生物科技有限公司

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