THZ-P1-2THZ-P1-2THZ-P1-2T39459 - 上海陶术生物科技有限公司

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产品名称：THZ-P1-2THZ-P1-2THZ-P1-2
产品型号：T39459
产品产地：中国大陆
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简介内容：THZ-P1-2 is a novel, specific inhibitor of PI5P4K that effectively targets PI5P4Kα. With an IC 50 of 190 nM, THZ-P1-2 selectively inhibits PI5P4Kα by forming covalent bonds with cysteine residues located on a disordered loop present in PI5P4Kα/β/γ. This mechanism not only disrupts autophagy but also elevates TFEB signaling. Moreover, THZ-P1-2 exhibits potent anticancer effects in leukemia cell lines, making it a promising candidate for therapeutic applications.

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原创作者：上海陶术生物科技有限公司

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