简介内容:PI3Kδ-IN-8 is a powerful and specific oral inhibitor of PI3Kδ, exhibiting an IC50 of nM. It demonstrates preferential inhibition of PI3Kδ when compared to PI3Kα, PI3Kβ, and PI3Kγ, with IC50 values of nM, nM, and nM, respectively. Furthermore, PI3Kδ-IN-8 possesses notable anti-tumor efficacy.