AP14145 hydrochloride；AP14145 hydrochlorideAP14145 hydrochlorideT39963

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产品名称：AP14145 hydrochloride；AP14145 hydrochlorideAP14145 hydrochloride
产品型号：T39963
产品产地：中国大陆
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简介内容：AP14145 hydrochloride is a potent negative allosteric modulator of K Ca 2 (SK) channels, specifically targeting K Ca (SK2) and K Ca (SK3) channels with an IC 50 of μM. Inhibition of AP14145 hydrochloride is highly influenced by S508 and A533 amino acids present in the channel. This compound effectively extends the atrial effective refractory period (AERP) in rats and exhibits antiarrhythmic properties in a Vernakalant-resistant porcine model of atrial fibrillation (AF).

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名称: AP14145 hydrochloride；AP14145 hydrochloride

描述: AP14145 hydrochloride。

关键字: AP14145 hydrochloride |

原创作者：上海陶术生物科技有限公司

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