Cambinol；化合物CambinolSIRT1/2 Inhibitor IV|||NSC 112546；SIRT1/2 Inhibitor IV|||NSC 112546T4019

当前位置:上海陶术生物科技有限公司>产品中心>活性小分子抑制剂 > Cambinol；化合物CambinolSIRT1/2 Inhibitor IV|||NSC 112546；SIRT1/2 Inhibitor IV|||NSC 112546

联系我们

产品目录

仪器耗材

天然产物

试剂盒

介绍

产品展示/Products

产品名称：Cambinol；化合物CambinolSIRT1/2 Inhibitor IV|||NSC 112546；SIRT1/2 Inhibitor IV|||NSC 112546
产品型号：T4019
产品产地：中国大陆
采购热度：
简介内容：Cambinol (SIRT1/2 Inhibitor IV) is a cell-permeable b-naphthol compound that inhibits the NAD-dependent deacetylase activity of SIRT1/2 (IC50: 56/59 μM, respectively) in a substrate-, but not NAD-, competitive manner. Cambinol inhibits SIRT5 deacetylase activity only at much higher concentrations (IC50 >300 μM) and no inhibitory for the class I and II HDACs. In BCL6-expressing Burkitt lymphoma cell lines, Cambinol-induced apoptosis has been attributed to the hyperacetylation of p53 and

详细内容/Content

原创作者：上海陶术生物科技有限公司

Cambinol；化合物CambinolSIRT1/2 Inhibitor IV|||NSC 112546；SIRT1/2 Inhibitor IV|||NSC 112546产品询价/message

同类相关产品/congeneric Product

4008200310

15002134094

工作时间

9:00-18:00

展开客服

第5年