ND1-YL2；ND1-YL2ND1-YL2；ND1-YL2T41146 - 上海陶术生物科技有限公司

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产品名称：ND1-YL2；ND1-YL2ND1-YL2；ND1-YL2
产品型号：T41146
产品产地：中国大陆
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简介内容：ND1-YL2 is a peptide-based PROTAC?Degrader of steroid receptor co-activator 1 (SRC-1; also known as nuclear receptor coactivator 1, NCOA1). ND1-YL2 is composed of a stapled peptide that binds SRC-1 (YL2) joined by a linker to a tetrapeptide that binds UBR box domains. Upon ternary complex formation, SRC-1 is polyubiquitinated and subsequently degraded via the N-degron pathway. This Degrader induces dose-dependent degradation of SRC-1 in the MDA-MB-231 triple negative breast cancer cell line (DC5

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名称: ND1-YL2；ND1-YL2

描述: ND1-YL2。

关键字: ND1-YL2；ND1-YL2 |

原创作者：上海陶术生物科技有限公司

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