Endoxifen；N-去甲基-4-羟基-(E/Z)-N-desmethyl-4-hydroxy Tamoxifen|||(E/Z)-Endoxifen；(E/Z)-N-desmethyl-4-hydT4281

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产品名称：Endoxifen；N-去甲基-4-羟基-(E/Z)-N-desmethyl-4-hydroxy Tamoxifen|||(E/Z)-Endoxifen；(E/Z)-N-desmethyl-4-hyd
产品型号：T4281
产品产地：中国大陆
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简介内容：(E/Z)-Endoxifen ((E/Z)-Endoxifen) is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-estrogen, as it has an approximately 100-fold greater affinity for estrogen receptors than tamoxifen. As the efficient conversion of tamoxifen to endoxifen depends on CYP2D6, polymorphisms in this CYP isoform can impact the effectiveness of TMX treatment.

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原创作者：上海陶术生物科技有限公司

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