Syk Inhibitor II dihydrochloride；化合物Syk Inhibitor II (hydrochloride)Syk Inhibitor II (hydrochloride)T4391

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产品名称：Syk Inhibitor II dihydrochloride；化合物Syk Inhibitor II (hydrochloride)Syk Inhibitor II (hydrochloride)
产品型号：T4391
产品产地：中国大陆
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简介内容：Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that, upon phosphorylation, binds to immunoreceptor tyrosine-based activation motifs of FcRγ chains and mediates downstream signaling related to platelet function and inflammation. Syk inhibitor II is a cell-permeable, pyrimidine-carboxamide compound that selectively and reversibly blocks Syk (IC50 = 41 nM) in an ATP-competitive manner. It is much less potent against PKCε, PKCβII, ZAP-70, Btk, and Itk (IC50s = , 11, , , an

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原创作者：上海陶术生物科技有限公司

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