MMRi62；化合物T602027-[(2,3-dichlorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol；7-[(2,3-dichlorophenT60202

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产品名称：MMRi62；化合物T602027-[(2,3-dichlorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol；7-[(2,3-dichlorophen
产品型号：T60202
产品产地：中国大陆
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简介内容：MMRi62 (7-[(2,3-dichlorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol), a ferroptosis inducer targeting MDM2-MDM4 (negative regulators of tumor suppressor p53). MMRi62 shows a P53-independent pro-apoptotic activity against pancreatic ductal adenocarcinoma (PDAC) cells and induce autophagy. MMRi62 inducesferroptosis, resulting in a increase of reactive oxygen and lysosomal degradation of ferritin heavy chain (FTH1). MMRi62 also leads to proteasomal degradation of mutant p53, also inhibits ortho

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原创作者：上海陶术生物科技有限公司

MMRi62；化合物T602027-[(2,3-dichlorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol；7-[(2,3-dichlorophen产品询价/message

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