简介内容:B-Raf IN 8 (compound 7g) is a potent inhibitor of B-Raf (IC 50 = nM). B-Raf IN 8 shows antitumor activity which has IC 50 values of , , and μM against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7) and human prostate cancer (PC-3) cells [1].