简介内容:MurB-IN-1 (compound 44) is a potent inhibitor of MurB, an essential enzyme involved in the synthesis of bacterial cell wall. With a binding affinity of K d μM, MurB-IN-1 effectively hinders the activity of MurB, presenting a promising therapeutic option against P. aeruginosa, a highly virulent and opportunistic pathogen associated with severe infections and mortality [1].