简介内容:PptT-IN-2 (compound 5k) is a highly effective inhibitor of phosphopantetheinyl phosphoryl transferase (PptT), with an IC50 of μM. PptT is an indispensable enzyme crucial for synthesizing cellular lipids and virulence factors in Mycobacterium tuberculosis. Therefore, PptT-IN-2 holds great promise for further investigations into tuberculosis research [1].