简介内容：S-777469 is a selective, orally active agonist of the cannabinoid type 2 receptor (CB2) (Ki: 36 nM). s-777469 significantly inhibited compound 48/80-induced scratching behaviour in mice in a dose-dependent manner. s-777469 excites CB2, inhibits pruritic signalling and shows an anti-pruritic effect.
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