XL888；化合物XL888XL888T6248 - 上海陶术生物科技有限公司

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产品名称：XL888；化合物XL888XL888
产品型号：T6248
产品产地：中国大陆
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简介内容：XL888 is an ATP-competitive inhibitor of Hsp90 ( IC50: 24 nM). Heat shock protein 90 (Hsp90) is a chaperone that maintains the functionality of client proteins involved in cell proliferation, cell cycling, and apoptosis. Through this action, specific client proteins are degraded, resulting in cell cycle arrest or apoptosis. XL888 is orally bioavailable and shows efficacy in tumor regression in gastric carcinoma and melanoma xenografts in mice.

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原创作者：上海陶术生物科技有限公司

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