简介内容:BChE-IN-8 (compound 20) is an orally active BChE (butyrylcholinesterase) inhibitor that crosses the blood-brain barrier and acts on eqBChE (IC50: nM), hBChE (IC50: nM). BChE-IN-8 can be used in the study of Alzheimer´s disease (AD), where it can exert neuroprotective and cognitive improvement effects through a variety of regulatory mechanisms, including the cholinergic system, Aβ aggregation and neuropeptide levels.