简介内容：BChE-IN-8 (compound 20) is an orally active BChE (butyrylcholinesterase) inhibitor that crosses the blood-brain barrier and acts on eqBChE (IC50: nM), hBChE (IC50: nM). BChE-IN-8 can be used in the study of Alzheimer´s disease (AD), where it can exert neuroprotective and cognitive improvement effects through a variety of regulatory mechanisms, including the cholinergic system, Aβ aggregation and neuropeptide levels.
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