简介内容:JAK-IN-23 is an orally active dual JAK/STAT and NF-κB inhibitor that inhibits J AK1 (IC50: nM), J AK2 (IC50: 15 nM), and J AK3 (IC50: nM). JAK-IN-23 exhibits strong anti-inflammatory effects and can reduce the release of various pro-inflammatory can be used to study inflammatory bowel disease (IBD).