简介内容:ATR-IN-11 (Compound Hit01) is a potent inhibitor of ataxia capillaris and Rad3-related (ATR) kinases. ATR-IN-11 is a promising lead compound for the discovery of subsequent drugs targeting the ATR kinase, a key regulatory protein in the DNA damage response (DDR) responsible for sensing replication stress (RS). ATR-IN-11 has potential for cancer disease research.