简介内容:NSD2-IN-1 (compound 38) serves as a potent and highly selective inhibitor of NSD2-PWWP1 (nuclear receptor-binding SET domain 2-PWWP1), demonstrating an IC50 value of μM. By binding to NSD2-PWWP1, NSD2-IN-1 impacts the expression of genes under NSD2 regulation, leading to apoptosis and cell cycle arrest [1].