简介内容:Henatinib is an orally active small molecule multi-kinase inhibitor with broad antitumour effects. henatinib inhibits the activity of VEGFR-2 (IC50: nM), c-kit (IC50: nM), PDGFR (IC50: nM). henatinib significantly inhibits VEGFR-2 phosphorylation and its downstream signalling pathways in human umbilical vein endothelial cells (HUVECs). Henatinib significantly inhibited VEGFR-2 phosphorylation and its downstream signaling pathway in human umbilical vein endothelial cells (HUVECs).