简介内容:HPK1-IN-3 is a selective, potent, ATP-competitive inhibitor of hematopoietic progenitor cell kinase 1 (HPK1; MAP4K1) (IC50: nM). HPK1-IN-3 has IL-2 cellular potency and is able to act on human peripheral blood mononuclear cells (PBMC) with an EC50 value of 108 nM.