简介内容:DHFR-IN-1 is a selective and potent inhibitor of DHFR (dihydrofolate reductase) (IC50: nM). DHFR-IN-1 exhibited some antifungal activity and good antibacterial activity against Gram-positive and Gram-negative showed good synergy with Levofloxacin with FIC (partial inhibitory concentration index) = .