简介内容：PKRA83 is a potent prokineticin (PK2) antagonist that crosses the blood-brain barrier and competes for PK2 binding to its receptors PKR1 and PKR2. PKRA83 effectively inhibits PK2 receptors and acts on PKR1 (IC50: nM) and PKR2 (IC50: nM). PKRA83 exhibits anti-cancer and anti-angiogenic effects.
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