简介内容：K20 is a potent and selective inhibitor of KRas G12C (IC50: nM). In H358 cells, K20 has an anticancer effect with an IC50 value of μM. K20 inhibits the growth of NCI-H358 tumor cells (TGI: 41%) without significant toxicity. k20 reduces the phosphorylation level of Erk, which leads to apoptosis.
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